Physiological challenging of stress in rats with zeaxanthin

Muthanna Medical Journal
Volume 9, Issue 1,  2022 Page 8-14

Wissam Sajid Hashim 1

Correspondence author:
Department of Physiology and medical Physics, College of Medicine, Al-Muthanna University 
Received 20 March 2022, Accepted 13 May 2022, Available online 16 May 2022
Copyright © 2022 WH . This is article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study was to rule whether the carotenoid zeaxanthin can withstand against the stress caused by hydrogen peroxide in rats. Three groups of twelve adult male Wistar rats were depended. The results hinted that zeaxanthin could significantly lower the elevated lipids LDL, TC, TAG, and VLDL caused by H2O2 and to elevate the HDL level. Besides, H2O2 caused a significant elevation in the serum anti-oxidant enzymes GPx, SOD, and CAT beside the stress marker MDA and when zeaxanthin was offered as a concomitant with H2O2, it caused a significant declination in these parameters.

Keywords: Stress, Zeaxanthin, Lutein, Lipids, Antioxidant enzymes