Harnessing the power of the Iraqi Hibiscus plant in cancer treatment

Posted on by Muthanna Medical Journal

Research article

Volume 10, Issue 2,  2023.  Page 250-257    10.52113/1/2/2023-250-257

Authors

Haider M. Badea Albadri 1, Yasir SJ Alrubaye 2* , Hassan Fadhil Alkitt 1

Correspondence author: Ph.yasiralrubaye@gmail.com
1 Department of Pharmaceutical Chemistry and Pharmacognosy, Department of Pharmacy, Baghdad College of Medical Science, Baghdad, Iraq.
2 Department of Clinical Pharmacy and Therapeutic, Department of Pharmacy, Baghdad College of Medical Science, Baghdad, Iraq.
Received 22 August 2023; revised 26 October 2023; accepted 30 November 2023, Published 30 December 2023.
Copyright © 2023 Yasir SJ Alrubaye. This is article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Abstract

According to World Health Organization (WHO), cancer accounted for approximately 9.6 million deaths in 2018, leading to nearly one in every six deaths worldwide. The rising prevalence of cancer necessitates transformative, efficient treatments that can improve the health status of patients as well as minimize the burden associated with this condition. One potential area in the search for cancer treatment comes with exploring naturally occurring compounds from plants. In the past few years, some researchers have focused their research on plants that may potentially possess anti-cancer properties including Iraqi hibiscus (Hibiscus sabdariffa L.). In this paper, we aim to present the up-to-date knowledge concerning anticancer activities of Iraqi hibiscus plant, possible mechanisms of action and clinical potentiality on behalf of this auspicious natural target. Varieties of bioactive compounds such as flavonoids, anthocyanins, and phenolic acids were found to be present in the Iraqi hibiscus plant with therapeutic potential composed of antioxidant; anti-inflammatory and anticancer activities. In conclusion, the future of hibiscus plant in cancer treatment in Iraq is very rosy with more research and development opportunities as well as integration into conventional cancer therapies.

Keywords: Anthocyanins, Cancer, Hibiscus, Flavonoids, Histopathological

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Albadri HA, Alrubaye Y, Alkitt HF. Harnessing the power of the Iraqi hibiscus plant in cancer treatment. Muthanna Medical Journal. 2023; 10(2):258-268.