Impact of obesity on spirometric parameters in asthmatic

Posted on by Muthanna Medical Journal

Research article

Volume 11, Issue 2,  2024.  Page 104-113    10.52113/1/1/2024-2-113

Authors
Hawraa Fadhil Abdulameer *1, Oday Taher Mohammed, Mohammed Waheeb Salman Al-Obaidi    

*Correspondence author: hawraa.abd2202d@comed.uobaghdad.edu.iq

*1 College of Medicine, University of Baghdad, Baghdad, Iraq.
 Received 12 July 2024; revised 11 August 2024; accepted 13 September 2024, available online 04 October 2024.
Copyright © 2024 Abdulameer, et al. This is article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Abstract

Obesity is a public health issue and a risk factor and disease modifier for juvenile and adult asthma. Due to the high prevalence of obesity and asthma, this connection may worsen asthma burden in individuals and populations. The extent to which obesity impressing lung function still vague. This research focus on impact of obesity on asthmatic spirometric parameters. Aim of the study: To determine the effect of obesity on spirometry parameters in asthmatic patients. 93 asthmatic patients are enrolled in this cross-sectional study. The diagnosis of asthma was made clinically and by PFT. The study done in Baghdad teaching hospital from 6 June 2023 to 16 January 2024. 45 (48.3%) of the 93 patients are classified as obese (BMI>=30) according to CDD.69.9% are female and 30.1% are male. Patients with a BMI ≥30 had a considerably older mean age (43.86 years vs. 38.27 years) and a higher mean PEFR% (52.37% vs. 43.39%) than those with a BMI less than 30. BMI is significantly correlated with FEF25-75, age, sex, and PEFR%. There is no statistically significant correlation observed between BMI and other parameters. Additionally, it was observed that females exhibited a higher FEF25-75% (a significant correlation between gender and FEF25-75%). This study shows that asthmatics, especially women, are obese. Different spirometric characteristics connected with BMI. FEF25-75 and PEFR % correlated, whereas others did not. In obese asthmatics, dysanapsis is a leading explanation for this observation. Obesity worsens asthma severity, exacerbations, and medication responsiveness, despite this favorable connection of several PFT variables to BMI.

Keywords: Prevalence, obesity, asthmatic, effects, spirometric, parameters

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Volume 11, Issue 2, 2024

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Abdulameer H, Al-Obaidi MW, Mohammed O. Impact of obesity on spirometric parameters in asthmatic . Muthanna Medical Journal. 2024; 11(2):94-113.