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Article Type

Article

Abstract

The redox properties of Helichrysum were studied in human blood using cyclic voltammetry (CV). The study aimed to determine the redox capacity of the phytochemicals in this herb, particularly phenolic compounds and flavonoids, and their effect on the redox balance in the blood. Voltographic plots showed distinct anodic and cathodic peaks at 750 and -600 mV, respectively, consistent with the redox activity of the active metabolites. The results indicated that Helichrysum exhibits a reversible redox process with significant antioxidant capacity, suggesting its role as an electron donor in biological systems. These findings contribute to understanding the electrochemical properties of medicinal plants in biological environments. This study investigates the redox behavior of Helichrysum extract in blood using cyclic voltammetry (CV) to evaluate its electrochemical and antioxidant properties, particularly at different concentrations, scan rates, and pH levels, and its biological effects. The variation in scan rate and pH revealed that the redox response of the helichrysome components is diffusely controlled and sensitive to environmental conditions, with enhanced oxidation peaks observed at physiological pH (7.6). The reproducibility of current responses through repeated scans confirmed the system's reliability and stability, while minimal electrode contamination indicated that the primary redox actives, likely phenols and flavonoids, undergo stable electron transport. These results suggest that helichrysome possesses strong antioxidant potential and is capable of maintaining redox balance within biological matrices. Overall, cyclic potential characterization provides an effective method for evaluating the redox dynamics of herbal compounds in complex fluids such as blood. This study contributes to understanding the electrochemical basis of helichrysome's biological activity and supports its potential therapeutic importance as a natural source of antioxidants.

Keywords

Helichrysum oil, Cyclic voltammetry, Redox behavior, Blood matrix, Antioxidant, Phenolic compounds

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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