Copyright © 2023 Yasir SJ Alrubaye. This is article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
According to World Health Organization (WHO), cancer accounted for approximately 9.6 million deaths in 2018, leading to nearly one in every six deaths worldwide. The rising prevalence of cancer necessitates transformative, efficient treatments that can improve the health status of patients as well as minimize the burden associated with this condition. One potential area in the search for cancer treatment comes with exploring naturally occurring compounds from plants. In the past few years, some researchers have focused their research on plants that may potentially possess anti-cancer properties including Iraqi hibiscus (Hibiscus sabdariffa L.). In this paper, we aim to present the up-to-date knowledge concerning anticancer activities of Iraqi hibiscus plant, possible mechanisms of action and clinical potentiality on behalf of this auspicious natural target. Varieties of bioactive compounds such as flavonoids, anthocyanins, and phenolic acids were found to be present in the Iraqi hibiscus plant with therapeutic potential composed of antioxidant; anti-inflammatory and anticancer activities. In conclusion, the future of hibiscus plant in cancer treatment in Iraq is very rosy with more research and development opportunities as well as integration into conventional cancer therapies.
Keywords: Anthocyanins, Cancer, Hibiscus, Flavonoids, Histopathological